CD86 抗体
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北京 101111
Quick Overview for CD86 抗体 (ABIN6296200)
抗原
See all CD86 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Mouse anti-Human/Mouse/Rat CD86 Antibody [Sodium Azide Free]
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特异性
- Cytoplasmic, membrane
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纯化方法
- ARH-77 (B-lymphoblastoid cell line) was used as the immunogen for this CD86 antibody.
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免疫原
- ARH-77 (B-lymphoblastoid cell line) was used as the immunogen for this CD86 antibody.
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anti-CD86 (CD86) (AA 140-175) antibody
CD86 适用: 人, 小鼠, 大鼠, 犬 FACS, WB, ELISA, IHC (fro), ICC, IHC (p), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-CD86 (CD86) (AA 37-272) antibodyCD86 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD86 (CD86) antibodyCD86 适用: 人 FACS, WB, IHC, IF, ELISA 宿主: 兔 Monoclonal C86-2160R unconjugated Recombinant Antibody
anti-CD86 (CD86) antibodyCD86 适用: 人 FACS, IHC, IF, Func 宿主: 小鼠 Monoclonal BU63 unconjugated
anti-CD86 (CD86) (AA 31-245) antibodyCD86 适用: 人 FACS, WB, IP, ICC 宿主: 兔 Monoclonal BLR029F unconjugated Recombinant Antibody
anti-CD86 (CD86) (AA 30-247) antibodyCD86 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-CD86 (CD86) antibodyCD86 适用: 人 FACS, WB, IP, IHC (fro) 宿主: 小鼠 Monoclonal BU63 unconjugated
anti-CD86 (CD86) antibody (FITC)CD86 适用: 人 FACS 宿主: 小鼠 Monoclonal BU63 FITC
anti-CD86 (CD86) antibodyCD86 适用: 人, 小鼠, 大鼠 FACS, IHC, IF 宿主: 小鼠 Monoclonal rC86-1146 unconjugated Recombinant Antibody
anti-CD86 (CD86) antibodyCD86 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 小鼠 Monoclonal C86-1146 unconjugated
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应用备注
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FACS: 0.5-1 μg/million cells
IF: 1-2 μg/mL
IHC (FFPE): 1-2 μg/mL (1)
Prediluted format: incubate for 30 min at RT (2) -
限制
- 仅限研究用
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缓冲液
- In 1X PBS ( pH 7.4), BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- CD86
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别名
- T-lymphocyte activation antigen CD86
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背景
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Target Description: This antibody recognizes a protein of 70 kDa, which is identified as CD86 (HLDA V, WS Code BP BP072. HLDA V, WS Code A A109. HLDA VI, WS Code BP 95. HLDA VI, WS Code B CD86.9). CD86 is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes. CD86 expression is rapidly upregulated by Bcell specific stimuli with peak expression at 18 to 42 hours after stimulation. CD86, along with CD80/B71, is an important accessory molecule in Tcell co-stimulation via its interaction with CD28 and CD152/CTLA4. Since CD86 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response. It is also found on malignant Hodgkin and Reed Sternberg (HRS) cells in Hodgkin's disease.
Gene Symbol: CD86///CD28LG2
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基因ID
- 942
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UniProt
- P42081
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
抗原
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