Keratin 77 抗体
Quick Overview for Keratin 77 抗体 (ABIN6296176)
抗原
See all Keratin 77 (KRT77) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Rabbit anti-Human Recombinant Acidic Cytokeratin Antibody [Sodium Azide Free]
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特异性
- Cytoplasmic
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纯化方法
- An amino acid sequence common to acidic/type I keratins (1) was used as the immunogen for the recombinant Acidic Cytokeratin antibody.
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免疫原
- An amino acid sequence common to acidic/type I keratins (1) was used as the immunogen for the recombinant Acidic Cytokeratin antibody.
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应用备注
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Immunofluorescence: 1-2 μg/mL
Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT (3)
Prediluted IHC only format: incubate for 30 min at RT (2)
FACS: 0.5-1 μg/million cells in 0.1ml
WB: 0.5-1 μg/mL -
限制
- 仅限研究用
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缓冲液
- In 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- Keratin 77 (KRT77)
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别名
- Keratin, type II cytoskeletal 1b
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背景
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Target Description: There are two types of cytokeratins/keratins/CKs: the acidic type I cytokeratins and the basic or neutral type II cytokeratins. The subsets of cytokeratins which an epithelial cell expresses depends mainly on the type of epithelium, the moment in the course of terminal differentiation and the stage of development. Thus this specific keratin fingerprint allows the classification of all epithelia upon their keratin expression profile. Furthermore this applies also to the malignant counterparts of the epithelia (carcinomas), as the keratin profile tends to remain constant when an epithelium undergoes malignant transformation. The main clinical implication is that the study of the keratin profile by immunohistochemistry techniques is a tool of immense value widely used for tumor diagnosis and characterization in surgical pathology. [Wiki]
Gene Symbol: KRT77///KRT1B
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基因ID
- 374454
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UniProt
- Q7Z794
抗原
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