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VCAM1 抗体

This anti-VCAM1 antibody is a 小鼠 单克隆 antibody detecting VCAM1 in FACS, IF, Func 和 BP. Suitable for 人.
产品编号 ABIN6296140
发货至: 中国

Quick Overview for VCAM1 抗体 (ABIN6296140)

抗原

See all VCAM1 抗体
VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This VCAM1 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func), Blocking Peptide (BP)
  • 原理

    Mouse anti-Human VCAM1 Antibody [Sodium Azide Free]

    特异性

    Cytoplasmic, membrane

    纯化方法

    Activated human umbilical vein endothelial cells (HUVEC) were used as the immunogen for the VCAM1 antibody.

    免疫原

    Activated human umbilical vein endothelial cells (HUVEC) were used as the immunogen for the VCAM1 antibody.
  • 应用备注

    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
    Immunofluorescence: 1-2 μg/mL
    Functional blocking: order BSA/azide free format

    限制

    仅限研究用
  • 缓冲液

    In 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原

    VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))

    别名

    Vascular cell adhesion protein 1

    背景

    Target Description: Recognizes a protein of 110 kDa, identified as CD106 (also known as vascular cell adhesion molecule-1 (VCAM-1), L1CAM and INCAM-100). It is a member of the Ig superfamily of adhesion molecules and is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on un-stimulated endothelial cells. It is also present on follicular and inter-follicular dendritic cells of lymph nodes, myoblasts, and some macrophages. L1CAM serves as a ligand for leukocyte integrin (VLA-4 or CD49d/CD29) and mediates cell adhesion of leukocytes to activated endothelium. It plays a role in various immunological and inflammatory responses. This mAb inhibits the binding of leukocytes to L1CAM on stimulated endothelial cells.

    Gene Symbol: VCAM1

    基因ID

    7412

    UniProt

    P19320

    途径

    Carbohydrate Homeostasis
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