Fibronectin 抗体
Quick Overview for Fibronectin 抗体 (ABIN6296126)
抗原
See all Fibronectin 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Mouse anti-Human/Pig/Mouse/Rat Fibronectin Antibody [Sodium Azide Free]
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特异性
- Connective tissue matrix
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纯化方法
- A T-cell lymphoma biopsy was used as the immunogen for this fibronectin antibody.
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免疫原
- A T-cell lymphoma biopsy was used as the immunogen for this fibronectin antibody.
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应用备注
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FACS: 0.5-1 μg/million cells
IF: 0.5-1 μg/mL
IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1) -
限制
- 仅限研究用
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缓冲液
- In 1X PBS ( pH 7.4), BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- Fibronectin
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背景
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Target Description: Fibronectin is a soluble dimeric glycoprotein of 440 kDa, which is present in cells, extracellular matrix, and blood. There are two types of fibronectin: soluble fibronectin which is produced by hepatocytes and found in blood plasma, and insoluble cellular fibronectin which is produced by fibroblasts in a soluble form and latter assembled into an insoluble form via fibril formation.This antibody reacts with the cellular as well as plasma form of fibronectin. Reportedly, after iv administration, this antibody localizes to tumor vessels where it binds to the underlying basement. The Fibronectin epitope recognized by this antibody is not accessible in normal tissues to the circulating antibody indicating that it can be used to specifically target tumor vessels in vivo. Clone TV-1 fibronectin antibody is reportedly useful for delivering vasoactive agents to tumors to induce increased vascular permeability or blood flow prior to treatment with chemotherapeutic drugs or antibodies.
Gene Symbol: FN1///FN
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基因ID
- 2335
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UniProt
- P02751
抗原
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