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Desmoglein 1 抗体

The 小鼠 单克隆 anti-Desmoglein 1 antibody is suitable to detect Desmoglein 1 in samples from 人. It has been validated for WB, IF, FACS 和 IP.
产品编号 ABIN6296099
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Desmoglein 1 抗体 (ABIN6296099)

抗原

See all Desmoglein 1 (DSG1) 抗体
Desmoglein 1 (DSG1)

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Desmoglein 1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunoprecipitation (IP)
  • 原理

    Mouse anti-Human Desmoglein 1 Antibody / DSG1 [Sodium Azide Free]

    特异性

    Cell surface

    纯化方法

    A recombinant protein corresponding to the intracellular domain of human Desmoglein 1 was used as the immunogen for the Desmoglein antibody.

    免疫原

    A recombinant protein corresponding to the intracellular domain of human Desmoglein 1 was used as the immunogen for the Desmoglein antibody.
  • 应用备注

    FACS: 0.5-1 μg/million cells in 0.1ml
    Immunofluorescence: 1-2 μg/mL
    WB: 0.5-1 μg/mL
    Immunoprecipitation: suitable

    限制

    仅限研究用
  • 缓冲液

    In 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原

    Desmoglein 1 (DSG1)

    别名

    Desmoglein-1

    背景

    Target Description: Desmoglein 1 (DSG1) is a member of the desmosomal cadherin family. Desmosomes are intercellular adhering junctions that represent cell surface attachment sites for intermediate filament. Desmocollins and desmogleins are the main desmosomal transmembrane proteins. Desmogleins consist of Dsg1, Dsg2, Dsg3, and Dsg4 isoforms. Within the desmosome, the extracellular domain of desmoglein is essential for calcium dependent heterophilic binding to the desmocollins, whereas the intracellular domain is essential for binding to the desmosomal plaque protein, plakoglobin. Desmoglein 1 is synthesized exclusively in the suprabasal layers. Intact and functionally active desmoglein 1 is essential to epidermal integrity.

    Gene Symbol: DSG1///CDHF4

    基因ID

    1828

    UniProt

    Q02413

    途径

    Cell-Cell Junction Organization
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