Desmoglein 1 抗体
Quick Overview for Desmoglein 1 抗体 (ABIN6296099)
抗原
See all Desmoglein 1 (DSG1) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Mouse anti-Human Desmoglein 1 Antibody / DSG1 [Sodium Azide Free]
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特异性
- Cell surface
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纯化方法
- A recombinant protein corresponding to the intracellular domain of human Desmoglein 1 was used as the immunogen for the Desmoglein antibody.
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免疫原
- A recombinant protein corresponding to the intracellular domain of human Desmoglein 1 was used as the immunogen for the Desmoglein antibody.
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应用备注
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FACS: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL
WB: 0.5-1 μg/mL
Immunoprecipitation: suitable -
限制
- 仅限研究用
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缓冲液
- In 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- Desmoglein 1 (DSG1)
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别名
- Desmoglein-1
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背景
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Target Description: Desmoglein 1 (DSG1) is a member of the desmosomal cadherin family. Desmosomes are intercellular adhering junctions that represent cell surface attachment sites for intermediate filament. Desmocollins and desmogleins are the main desmosomal transmembrane proteins. Desmogleins consist of Dsg1, Dsg2, Dsg3, and Dsg4 isoforms. Within the desmosome, the extracellular domain of desmoglein is essential for calcium dependent heterophilic binding to the desmocollins, whereas the intracellular domain is essential for binding to the desmosomal plaque protein, plakoglobin. Desmoglein 1 is synthesized exclusively in the suprabasal layers. Intact and functionally active desmoglein 1 is essential to epidermal integrity.
Gene Symbol: DSG1///CDHF4
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基因ID
- 1828
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UniProt
- Q02413
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途径
- Cell-Cell Junction Organization
抗原
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