RNMT 抗体
Quick Overview for RNMT 抗体 (ABIN6296037)
抗原
See all RNMT 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Mouse anti-Human/Cow/Dog/Hamster/Rat TAG-72 Antibody [Sodium Azide Free]
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特异性
- Cytoplasmic and cell surface
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纯化方法
- A membrane-enriched fraction of a human breast carcinoma liver metastasis was used as the immunogen for this TAG-72 antibody.
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免疫原
- A membrane-enriched fraction of a human breast carcinoma liver metastasis was used as the immunogen for this TAG-72 antibody.
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应用备注
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Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL
Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
Prediluted format: incubate for 30 min at RT (2) -
限制
- 仅限研究用
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缓冲液
- In 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- RNMT (RNA Guanine-7 Methyltransferase (RNMT))
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别名
- mRNA cap guanine-N7 methyltransferase
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背景
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Target Description: Recognizes an oncofetal antigen of 220 kDa, identified as a Tumor-associated glycoprotein (TAG-72) with properties of a mucin. This mAb defines the mucin-carried sialylated-Tn epitope. TAG72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80 % sensitivity and 93 % specificity for pulmonary adenocarcinoma. Therefore, TAG72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of anti-TAG72 and anti-GCDFP-15 is valuable in the diagnosis of apocrine carcinoma.
Gene Symbol: tag-72 C25A1.3
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基因ID
- 182875
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UniProt
- Q9XVS1
抗原
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