RNMT 抗体
Quick Overview for RNMT 抗体 (ABIN6296035)
抗原
See all RNMT 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Mouse anti-Human/Cow/Dog/Rat TAG-72 Antibody Cocktail [IHC only]
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特异性
- Cytoplasmic and cell surface
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纯化方法
- A membrane-enriched fraction of a human breast carcinoma liver metastasis (B72.3) and purified TAG-72 protein (CC49) were used as the immunogens for this TAG-72 antibody cocktail.
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免疫原
- A membrane-enriched fraction of a human breast carcinoma liver metastasis (B72.3) and purified TAG-72 protein (CC49) were used as the immunogens for this TAG-72 antibody cocktail.
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anti-RNA Guanine-7 Methyltransferase (RNMT) (AA 1-476) antibody
RNMT 适用: 人 WB, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3H3-1D12 unconjugated
anti-RNA Guanine-7 Methyltransferase (RNMT) (AA 326-375) antibodyRNMT 适用: 人, 大鼠, Cow, 犬, 小鼠, 马, 豚鼠, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-RNA Guanine-7 Methyltransferase (RNMT) (AA 108-157) antibodyRNMT 适用: 人, 马, 兔, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-RNA Guanine-7 Methyltransferase (RNMT) (C-Term) antibodyRNMT 适用: 人, 大鼠, Cow, 犬, 小鼠, 马, 豚鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-RNA Guanine-7 Methyltransferase (RNMT) (N-Term) antibodyRNMT 适用: 人, Cow, 犬, 马, 豚鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Prediluted format : incubate for 30 min at RT (2)
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限制
- 仅限研究用
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缓冲液
- Prediluted in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- RNMT (RNA Guanine-7 Methyltransferase (RNMT))
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别名
- mRNA cap guanine-N7 methyltransferase
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背景
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Target Description: Recognizes an oncofetal antigen of 220 kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This mAb defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80 % sensitivity and 93 % specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of anti-TAG-72 and anti-GCDFP-15 is valuable in the diagnosis of apocrine carcinoma.
Gene Symbol: tag-72 C25A1.3
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基因ID
- 182875
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UniProt
- Q9XVS1
抗原
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