DPP4 抗体
Quick Overview for DPP4 抗体 (ABIN6296016)
抗原
See all DPP4 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Mouse anti-Human/Rat CD26 Antibody [Sodium Azide Free]
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特异性
- Cell surface
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纯化方法
- A human T cell clone was used as the immunogen for the CD26 antibody.
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免疫原
- A human T cell clone was used as the immunogen for the CD26 antibody.
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应用备注
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Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
Immunohistochemistry (Frozen Only): 0.5-1 μg/mL for 30 min at RT -
限制
- 仅限研究用
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缓冲液
- In 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- DPP4 (Dipeptidyl-Peptidase 4 (DPP4))
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别名
- Dipeptidyl peptidase 4 ]
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背景
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Target Description: Recognizes a glycoprotein of 110 kDa, identified as CD26 (Workshop VI, Code: N-L039). It is an atypical serine protease belonging to the prolyl oligopeptidase family. It is expressed on lymphocyte cells and is upregulated during T-cell activation. CD26 is also expressed on activated B cells and natural killer cells and abundantly on epithelia. CD26 is implicated in a variety of biological functions including T-cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection. Cross-linking of CD26 using this antibody dramatically enhances the anti-CD3-induced IL-2 production. In Western blotting, this mAb reacts with only glycosylated CD26, but not with the deglycosylated form. It does not prevent ADA binding to CD26.
Gene Symbol: DPP4///ADCP2///CD26
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基因ID
- 1803
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UniProt
- P27487
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途径
- Peptide Hormone Metabolism, Regulation of Leukocyte Mediated Immunity
抗原
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