CRYAB 抗体 (C-Term)
Quick Overview for CRYAB 抗体 (C-Term) (ABIN629589)
抗原
See all CRYAB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- Crystallin Alpha B antibody was raised against the C terminal of CRYAB
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纯化方法
- Purified
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免疫原
- Crystallin Alpha B antibody was raised using the C terminal of CRYAB corresponding to a region with amino acids KYRIPADVDPLTITSSLSSDGVLTVNGPRKQVSGPERTIPITREEKPAVT
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应用备注
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WB: 5 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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Crystallin Alpha B Blocking Peptide, (ABIN940136), is also available for use as a blocking control in assays to test for specificity of this Crystallin Alpha B antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of CRYAB antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- CRYAB (Crystallin, alpha B (CRYAB))
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别名
- Crystallin alpha B
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背景
- Alpha crystallins are composed of: alpha-A and alpha-B, for acidic and basic, respectively. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone, instead they hold them in large soluble aggregates. Post-translational modifications decrease the ability to chaperone. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. Alpha-A and alpha-B are differentially expressed, alpha-A is preferentially restricted to the lens and alpha-B is expressed widely in many tissues and organs. Elevated expression of alpha-B crystallin occurs in many neurological diseases, a missense mutation cosegregated in a family with a desmin-related myopathy.
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分子量
- 12 kDa (MW of target protein)
抗原
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