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CRYAB 抗体 (C-Term)

This anti-CRYAB antibody is a 兔 多克隆 antibody detecting CRYAB in WB. Suitable for 人 和 小鼠.
产品编号 ABIN629589
发货至: 中国

Quick Overview for CRYAB 抗体 (C-Term) (ABIN629589)

抗原

See all CRYAB 抗体
CRYAB (Crystallin, alpha B (CRYAB))

适用

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人, 小鼠

宿主

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  • 48
  • 2
  • 1

克隆类型

  • 135
  • 57
多克隆

标记

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This CRYAB antibody is un-conjugated

应用范围

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  • 1
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Western Blotting (WB)
  • 抗原表位

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    C-Term

    特异性

    Crystallin Alpha B antibody was raised against the C terminal of CRYAB

    纯化方法

    Purified

    免疫原

    Crystallin Alpha B antibody was raised using the C terminal of CRYAB corresponding to a region with amino acids KYRIPADVDPLTITSSLSSDGVLTVNGPRKQVSGPERTIPITREEKPAVT
  • 应用备注

    WB: 5 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    Crystallin Alpha B Blocking Peptide, (ABIN940136), is also available for use as a blocking control in assays to test for specificity of this Crystallin Alpha B antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of CRYAB antibody in PBS

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原

    CRYAB (Crystallin, alpha B (CRYAB))

    别名

    Crystallin alpha B

    背景

    Alpha crystallins are composed of: alpha-A and alpha-B, for acidic and basic, respectively. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone, instead they hold them in large soluble aggregates. Post-translational modifications decrease the ability to chaperone. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. Alpha-A and alpha-B are differentially expressed, alpha-A is preferentially restricted to the lens and alpha-B is expressed widely in many tissues and organs. Elevated expression of alpha-B crystallin occurs in many neurological diseases, a missense mutation cosegregated in a family with a desmin-related myopathy.

    分子量

    12 kDa (MW of target protein)
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