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TGIF1 抗体 (N-Term)

This anti-TGIF1 antibody is a 兔 多克隆 antibody detecting TGIF1 in . Suitable for 人.
产品编号 ABIN6295868
发货至: 中国

Quick Overview for TGIF1 抗体 (N-Term) (ABIN6295868)

抗原

See all TGIF1 抗体
TGIF1 (TGFB-Induced Factor Homeobox 1 (TGIF1))

适用

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宿主

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克隆类型

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多克隆

标记

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This TGIF1 antibody is un-conjugated

应用范围

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  • 抗原表位

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    AA 81-109, N-Term

    原理

    Rabbit Anti-Human TGIF1 (N-term) Antibody

    免疫原

    This TGIF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-109 amino acids from the N-terminal region of human TGIF1.
  • 限制

    仅限研究用
  • 储存条件

    4 °C,-20 °C

    储存方法

    2-8°C (short-term), -20°C (long-term)
  • 抗原

    TGIF1 (TGFB-Induced Factor Homeobox 1 (TGIF1))

    别名

    TGIF1

    背景

    Target Description: The protein encoded by this gene is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain. Alternative splicing has been observed at this locus and eight variants, encoding four distinct isoforms, are described.

    Gene Symbol: TGIF1

    基因ID

    7050

    UniProt

    Q15583

    途径

    Retinoic Acid Receptor Signaling Pathway, Chromatin Binding, Tube Formation
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