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PAX6 抗体 (N-Term)

This anti-PAX6 antibody is a 小鼠 单克隆 antibody detecting PAX6 in IF, IHC 和 FACS. Suitable for 人.
产品编号 ABIN6295578
发货至: 中国
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Quick Overview for PAX6 抗体 (N-Term) (ABIN6295578)

抗原

See all PAX6 抗体
PAX6 (Paired Box 6 (PAX6))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This PAX6 antibody is un-conjugated

应用范围

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Immunofluorescence (IF), Immunohistochemistry (IHC), Flow Cytometry (FACS)
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    AA 1-300, N-Term

    原理

    Mouse anti-Human PAX-6 Antibody [Sodium Azide Free]

    特异性

    Nuclear

    纯化方法

    A recombinant fragment (N-terminus, aa 1-300) was used as the immunogen for the PAX-6 antibody.

    免疫原

    A recombinant fragment (N-terminus, aa 1-300) was used as the immunogen for the PAX-6 antibody.
  • 应用备注

    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
    Immunofluorescence: 0.5-1 μg/mL
    Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1)
    Prediluted format: incubate for 30 min at RT (2)

    限制

    仅限研究用
  • 缓冲液

    In 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原

    PAX6 (Paired Box 6 (PAX6))

    别名

    Paired box protein Pax-6

    背景

    Target Description: Pax genes contain paired domains with strong homology to genes in Drosophila, which are involved in programming early development. Lesions in the Pax-6 gene account for most cases of aniridia, a congenital malformation of the eye, chiefly characterized by iris hypoplasia, which can cause blindness. Pax-6 is involved in other anterior segment malformations besides aniridia, such as Peters anomaly, a major error in the embryonic development of the eye with corneal clouding with variable iridolenticulocorneal adhesions. The Pax-6 gene encodes a transcriptional regulator that recognizes target genes through its paired-type DNA-binding domain. The paired domain is composed of two distinct DNA-binding subdomains, the amino-terminal subdomain and the carboxy-terminal subdomain, which bind respective consensus DNA sequences. The human Pax-6 gene produces two alternatively spliced isoforms that have the distinct structure of the paired domain.

    Gene Symbol: PAX6///AN2

    基因ID

    5080

    UniProt

    P26367

    途径

    Peptide Hormone Metabolism, Carbohydrate Homeostasis
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