CLTA 抗体 (N-Term)
Quick Overview for CLTA 抗体 (N-Term) (ABIN6295474)
抗原
See all CLTA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- Mouse anti-Human Clatherin Light Chain Antibody (LCA/LCB) [Sodium Azide Free]
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特异性
- Cytoplasmic
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纯化方法
- A recombinant N-terminal protein fragment from human Clathrin light chain was used as the immunogen for the Clathrin Light Chain antibody.
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免疫原
- A recombinant N-terminal protein fragment from human Clathrin light chain was used as the immunogen for the Clathrin Light Chain antibody.
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应用备注
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Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL
WB: 0.5-1 μg/mL
IHC (FFPE): 0.5-1 μg/mL for 30 min at RT -
限制
- 仅限研究用
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缓冲液
- In 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- CLTA (Clathrin, Light Chain A (CLTA))
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别名
- Clathrin light chain A
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背景
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Target Description: Recognizes proteins of 31-44 kDa, which are identified as Clathrin Light Chains (both A & B). Clathrin is composed of three heavy chains and three light chains, which associate non-covalently to form a triskelion structure. Clathrin light chain regulates the self-assembly of triskelions onto intracellular membranes. Clathrin light chain subunits (LCA and LCB) contribute to regulation of coated vesicle formation to sort proteins during receptor-mediated endocytosis and organelle biogenesis. LCA and LCB are encoded by two discrete genes. They share only 60 % homology, and have certain features in common. Both LCA and LCB undergo alternative mRNA splicing, which results in the generation of tissue-specific isoforms.
Gene Symbol: CLTA///CLTB
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UniProt
- P09496, P09497
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途径
- EGFR Signaling Pathway, Neurotrophin Signaling Pathway, EGFR Downregulation
抗原
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