CD56 抗体 (Extracellular Domain)
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Quick Overview for CD56 抗体 (Extracellular Domain) (ABIN6295451)
抗原
See all CD56 (NCAM1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Extracellular Domain
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原理
- Mouse anti-Human CD56 Antibody [Sodium Azide Free]
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特异性
- Cell surface
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纯化方法
- A membrane preparation of small cell lung carcinoma was used as the immunogen for this anti-CD56 antibody. This mAb reacts with an extracellular domain (close to transmembrane) of CD56/NCAM.
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免疫原
- A membrane preparation of small cell lung carcinoma was used as the immunogen for this anti-CD56 antibody. This mAb reacts with an extracellular domain (close to transmembrane) of CD56/NCAM.
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应用备注
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Immunofluorescence: 1-2 μg/mL
Immunohistochemistry (FFPE): 1-2 μg/mL for 30 minutes at RT (1)
Prediluted format: incubate for 30 min at RT (2) -
限制
- 仅限研究用
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缓冲液
- In 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))
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别名
- Neural cell adhesion molecule 1
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背景
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Target Description: Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135 kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.
Gene Symbol: NCAM1///NCAM
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基因ID
- 4684
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UniProt
- P13591
抗原
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