LDL 抗体 (Center)
Quick Overview for LDL 抗体 (Center) (ABIN6295353)
抗原
See all LDL 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 391-419, Center
-
原理
- Rabbit Anti-LDLR (Center) Antibody
-
免疫原
- This LDLR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 391-419 amino acids from the Central region of human LDLR.
-
-
-
-
限制
- 仅限研究用
-
-
-
储存条件
- 4 °C,-20 °C
-
储存方法
- 2-8°C (short-term), -20°C (long-term)
-
-
- LDL (Low Density Lipoprotein (LDL))
-
别名
- LDL
-
背景
-
Target Description: The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place.
Gene Symbol: LDLR
-
基因ID
- 3949
-
UniProt
- P01130
抗原
-