SPHK1 抗体 (Center)
Quick Overview for SPHK1 抗体 (Center) (ABIN6295303)
抗原
See all SPHK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 286-315, Center
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原理
- Rabbit Anti-SPHK1 (Center) Antibody
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免疫原
- This SPHK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 286-315 amino acids from the Central region of human SPHK1.
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anti-Sphingosine Kinase 1 (SPHK1) (AA 1-384) antibody
SPHK1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D6 unconjugated
anti-Sphingosine Kinase 1 (SPHK1) (AA 286-315) antibodySPHK1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB03621 unconjugated
anti-Sphingosine Kinase 1 (SPHK1) (AA 313-343) antibodySPHK1 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine Kinase 1 (SPHK1) (AA 286-315) antibodySPHK1 适用: 人, 小鼠, 大鼠, 灵长类 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine Kinase 1 (SPHK1) (AA 148-398) antibodySPHK1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine Kinase 1 (SPHK1) (AA 1-384) antibodySPHK1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine Kinase 1 (SPHK1) (AA 50-384) antibodySPHK1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine Kinase 1 (SPHK1) (AA 1-30), (N-Term) antibodySPHK1 适用: 人 WB 宿主: 兔 Polyclonal RB3619 unconjugated
anti-Sphingosine Kinase 1 (SPHK1) (AA 59-89) antibodySPHK1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine Kinase 1 (SPHK1) (AA 1-30) antibodySPHK1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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限制
- 仅限研究用
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C (short-term), -20°C (long-term)
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- SPHK1 (Sphingosine Kinase 1 (SPHK1))
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别名
- SPHK1
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背景
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Target Description: Sphingosine Kinase (SphK) catalyzes the phosphorylation of the lipid sphingosine, creating the bioactive lipid sphingosine-1-phosphate (S1P). S1P subsequently signals through cell surface G protein-coupled receptors, as well as intracellularly, to modulate cell proliferation, survival, motility and differentiation. SphK is an important signaling enzyme which is activated by diverse agents, including growth factors that signal through receptor tyrosine kinases, agents activating G protein-coupled receptors, and immunoglobulin receptors. Two SphK isotypes, SphK-1 and SphK-2, have been cloned, and both isotypes are ubiquitously expressed. SphK-1 has been shown to mediate cell growth, prevention of apoptosis, and cellular transformation, and is upregulated in a variety of human tumors. In contrast, SphK-2 increases apoptosis, and may be responsible for phosphorylating and activating the immunosuppressive drug FTY720.
Gene Symbol: SPHK1
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基因ID
- 8877
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UniProt
- Q9NYA1
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途径
- VEGF Signaling
抗原
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