CSE1L 抗体 (C-Term)
Quick Overview for CSE1L 抗体 (C-Term) (ABIN6295024)
抗原
适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 55-84, C-Term
-
原理
- Rabbit Anti-Cellular Apoptosis Susceptibility (C-term) Antibody
-
免疫原
- This Cellular Apoptosis Susceptibility antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-84 amino acids from the C-terminal region of human Cellular Apoptosis Susceptibility.
-
-
-
-
限制
- 仅限研究用
-
-
-
储存条件
- 4 °C,-20 °C
-
储存方法
- 2-8°C (short-term), -20°C (long-term)
-
-
- CSE1L (Chromosome Segregation 1-Like (CSE1L))
-
别名
- Cellular Apoptosis Susceptibility
-
背景
-
Target Description: Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. CSE1L binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, CSE1L may play a role both in apoptosis and in cell proliferation.
Gene Symbol: CSE1L
-
基因ID
- 1434
-
UniProt
- P55060
抗原
-