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CSE1L 抗体 (C-Term)

This anti-CSE1L antibody is a 兔 多克隆 antibody detecting CSE1L in . Suitable for 人 和 小鼠.
产品编号 ABIN6295024
发货至: 中国

Quick Overview for CSE1L 抗体 (C-Term) (ABIN6295024)

抗原

CSE1L (Chromosome Segregation 1-Like (CSE1L))

适用

  • 9
  • 9
  • 7
人, 小鼠

宿主

  • 9

克隆类型

  • 7
  • 2
多克隆

标记

  • 2
  • 1
  • 1
  • 1
  • 1
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This CSE1L antibody is un-conjugated

应用范围

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  • 抗原表位

    AA 55-84, C-Term

    原理

    Rabbit Anti-Cellular Apoptosis Susceptibility (C-term) Antibody

    免疫原

    This Cellular Apoptosis Susceptibility antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-84 amino acids from the C-terminal region of human Cellular Apoptosis Susceptibility.
  • 限制

    仅限研究用
  • 储存条件

    4 °C,-20 °C

    储存方法

    2-8°C (short-term), -20°C (long-term)
  • 抗原

    CSE1L (Chromosome Segregation 1-Like (CSE1L))

    别名

    Cellular Apoptosis Susceptibility

    背景

    Target Description: Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. CSE1L binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, CSE1L may play a role both in apoptosis and in cell proliferation.

    Gene Symbol: CSE1L

    基因ID

    1434

    UniProt

    P55060
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