SUMO2 抗体 (C-Term)
Quick Overview for SUMO2 抗体 (C-Term) (ABIN6294661)
抗原
See all SUMO2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Mouse Anti-SUMO2 (C-term) Antibody
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免疫原
- Purified His-tagged SUMO2 protein was used to produced this monoclonal antibody.
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限制
- 仅限研究用
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C (short-term), -20°C (long-term)
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- SUMO2 (Small Ubiquitin Related Modifier 2 (SUMO2))
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别名
- SUMO2
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背景
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Target Description: Ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Polymeric SUMO2 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins.
Gene Symbol: SUMO2
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基因ID
- 6613
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UniProt
- P61956
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途径
- Methionine Biosynthetic Process
抗原
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