Ubiquitin Hydrolase Isozyme L1 (C-Term) 抗体
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Quick Overview for Ubiquitin Hydrolase Isozyme L1 (C-Term) 抗体 (ABIN6294653)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Mouse anti-Human/Mouse/Rat/Cow/Pig PGP9.5 Antibody UchL1 [Sodium Azide Free]
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特异性
- Cytoplasmic
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纯化方法
- Native protein from brain was used as the immunogen for this PGP9.5 antibody.
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免疫原
- Native protein from brain was used as the immunogen for this PGP9.5 antibody.
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应用备注
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WB: 0.5-1 μg/mL
IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
Prediluted format: incubate for 30 min at RT (2) -
限制
- 仅限研究用
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缓冲液
- In 1X PBS ( pH 7.4), BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- Ubiquitin Hydrolase Isozyme L1
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背景
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Target Description: This antibody specifically reacts with a protein of 20-30 kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1). Initially, expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. PGP9.5 antibody has been used to show the protein to be a useful prognostic indicator of colorectal, pancreatic and gall bladder cancer. A mutation in the gene is believed to cause a form of Parkinson's disease.
Gene Symbol: UCHL1
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基因ID
- 7345
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UniProt
- P09936
抗原
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