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Filaggrin 抗体 (AA 998-1104)

The 小鼠 单克隆 anti-Filaggrin antibody (ABIN6294618) specifically detects Filaggrin in IHC, IF 和 FACS. The antibody is reactive with 人 samples.
产品编号 ABIN6294618
发货至: 中国
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Quick Overview for Filaggrin 抗体 (AA 998-1104) (ABIN6294618)

抗原

See all Filaggrin (FLG) 抗体
Filaggrin (FLG)

适用

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宿主

  • 58
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小鼠

克隆类型

  • 58
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单克隆

标记

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This Filaggrin antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
  • 抗原表位

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    AA 998-1104

    原理

    Mouse anti-Human Filaggrin Antibody [Sodium Azide Free]

    特异性

    Cytoplasmic

    纯化方法

    Amino acids 998-1104 of human FLG were used as the immunogen for this Filaggrin antibody.

    免疫原

    Amino acids 998-1104 of human FLG were used as the immunogen for this Filaggrin antibody.
  • 应用备注

    FACS: 0.5-1 μg/10^6 cells in 0.1ml
    IF: 1-2 μg/mL
    IHC (FFPE): 0.5-1 μg/mL for 30 min at RT

    限制

    仅限研究用
  • 缓冲液

    In 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原

    Filaggrin (FLG)

    别名

    Filaggrin

    背景

    Target Description: Filaggrin (FLG) is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple Filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional Filaggrin molecules. Active Filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.

    Gene Symbol: FLG

    基因ID

    2312

    UniProt

    P20930

    途径

    Sensory Perception of Sound, Stem Cell Maintenance
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