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ANO1 抗体 (AA 904-986)

This anti-ANO1 antibody is a 小鼠 单克隆 antibody detecting ANO1 in IHC, IF 和 FACS. Suitable for 人.
产品编号 ABIN6294609
发货至: 中国

Quick Overview for ANO1 抗体 (AA 904-986) (ABIN6294609)

抗原

See all ANO1 抗体
ANO1 (Anoctamin 1, Calcium Activated Chloride Channel (ANO1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This ANO1 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
  • 抗原表位

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    AA 904-986

    原理

    Mouse anti-Human DOG-1 Antibody [Sodium Azide Free]

    特异性

    Cell Surface and Cytoplasm

    纯化方法

    Amino acids 904-986 from the human protein was used as the immunogen for this DOG-1 antibody.

    免疫原

    Amino acids 904-986 from the human protein was used as the immunogen for this DOG-1 antibody.
  • 应用备注

    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
    Immunofluorescence: 0.5-1 μg/mL
    Immunohistochemistry (FFPE): 0.25-0.5 μg/mL for 30 minutes at RT (1)
    Prediluted format: incubate for 30 min at RT (2)

    限制

    仅限研究用
  • 缓冲液

    In 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原

    ANO1 (Anoctamin 1, Calcium Activated Chloride Channel (ANO1))

    别名

    Anoctamin-1

    背景

    Target Description: Expression of DOG-1 protein is elevated in the gastrointestinal stromal tumors (GISTs), c-kit signaling-driven mesenchymal tumors of the GI tract. DOG-1 is rarely expressed in other soft tissue tumors, which, due to appearance, may be difficult to diagnose. Immunoreactivity for DOG-1 has been reported in 97.8 percent of scorable GISTs, including all c-kit negative GISTs. Overexpression of DOG-1 has been suggested to aid in the identification of GISTs, including Platelet-Derived Growth Factor Receptor Alpha mutants that fail to express c-kit antigen. The overall sensitivity of DOG1 and c-kit in GISTs is nearly identical: 94.4 % vs. 94.7 %.

    Gene Symbol: ANO1///DOG1///ORAOV2///TAOS2///TMEM16A

    基因ID

    55107

    UniProt

    Q5XXA6
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