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Myogenin 抗体 (AA 30-224)

This 小鼠 单克隆 anti-Myogenin antibody specifically detects Myogenin in IHC, FACS 和 IF. The antibody is reactive with 人, 小鼠, 大鼠, Pig 和 Cat samples.
产品编号 ABIN6294456
发货至: 中国
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Quick Overview for Myogenin 抗体 (AA 30-224) (ABIN6294456)

抗原

See all Myogenin (MYOG) 抗体
Myogenin (MYOG) (Myogenin (Myogenic Factor 4) (MYOG))

适用

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人, 小鼠, 大鼠, Pig, Cat

宿主

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小鼠

克隆类型

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单克隆

标记

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This Myogenin antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)
  • 抗原表位

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    AA 30-224

    原理

    Mouse anti-Human/Mouse/Rat/Cat/Pig Myogenin Antibody Cocktail [Sodium Azide Free]

    特异性

    Nuclear

    纯化方法

    Full length human recombinant protein (MGN185) and a partial rat recombinant protein (amino acid 30-224) (F5D) were used as the immunogens for this Myogenin antibody cocktail.

    免疫原

    Full length human recombinant protein (MGN185) and a partial rat recombinant protein (amino acid 30-224) (F5D) were used as the immunogens for this Myogenin antibody cocktail.
  • 应用备注

    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
    Immunofluorescence: 0.5-1 μg/mL
    Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
    Prediluted format: incubate for 30 min at RT (2)

    限制

    仅限研究用
  • 缓冲液

    In 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原

    Myogenin (MYOG) (Myogenin (Myogenic Factor 4) (MYOG))

    别名

    Myogenin

    背景

    Target Description: Myogenin is a member of the MyoD family of myogenic basic helix-loop-helix (bHLH) transcription factors that also includes MyoD, Myf-5, and MRF4 (also known as herculinor Myf-6). MyoD family members are expressed exclusively in skeletal muscle and play a key role in activating myogenesis by binding to enhancer sequences of muscle-specific genes. The regulatory domain of MyoD is approximately 70 amino acids in length and includes both a basic DNA binding motif and a bHLH dimerization motif. MyoD family members share about 80 % amino acid homology in their bHLH motifs. Anti-myogenin labels the nuclei of myoblasts in developing muscle tissue, and is expressed in tumor cell nuclei of rhabdomyosarcoma and some leiomyosarcomas. Positive nuclear staining may occur in Wilms tumor.

    Gene Symbol: MYOG///BHLHC3///MYF4

    基因ID

    4656

    UniProt

    P15173

    途径

    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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