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TEAD2 抗体 (Center)

The 兔 多克隆 anti-TEAD2 antibody (ABIN6294438) specifically detects TEAD2. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN6294438
发货至: 中国
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Quick Overview for TEAD2 抗体 (Center) (ABIN6294438)

抗原

See all TEAD2 抗体
TEAD2 (TEA Domain Family Member 2 (TEAD2))

适用

  • 37
  • 31
  • 5
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
人, 小鼠

宿主

  • 43
  • 8
  • 1

克隆类型

  • 46
  • 6
多克隆

标记

  • 26
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This TEAD2 antibody is un-conjugated

应用范围

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  • 抗原表位

    • 15
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 267-295, Center

    原理

    Rabbit Anti-TEAD2 (Center) Antibody

    免疫原

    This TEAD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 267-295 amino acids from the Central region of human TEAD2.
  • 限制

    仅限研究用
  • 储存条件

    4 °C,-20 °C

    储存方法

    2-8°C (short-term), -20°C (long-term)
  • 抗原

    TEAD2 (TEA Domain Family Member 2 (TEAD2))

    别名

    TEAD2

    背景

    Target Description: Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to the SPH and GT-IIC 'enhansons' (5'-GTGGAATGT-3'). May be involved in the gene regulation of neural development. Binds to the M-CAT motif.

    Gene Symbol: TEAD2

    基因ID

    8463

    UniProt

    Q15562

    途径

    Regulation of Lipid Metabolism by PPARalpha, Tube Formation
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