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TIMP3 抗体 (AA 175-211)

This anti-TIMP3 antibody is a 兔 多克隆 antibody detecting TIMP3 in WB, IHC, IP, FACS 和 IF. Suitable for 人, 小鼠, 大鼠, Cow, 犬 和 马.
产品编号 ABIN6294338
发货至: 中国

Quick Overview for TIMP3 抗体 (AA 175-211) (ABIN6294338)

抗原

See all TIMP3 抗体
TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))

适用

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人, 小鼠, 大鼠, Cow, 犬, 马

宿主

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克隆类型

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多克隆

标记

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This TIMP3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Flow Cytometry (FACS), Immunofluorescence (IF)
  • 抗原表位

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    AA 175-211

    原理

    Rabbit anti-Human/Mouse/Rat/Horse/Cow/Dog TIMP3 Antibody [Sodium Azide Free]

    特异性

    Cytoplasmic

    纯化方法

    Amino acids 175-211 of human TIMP3 Ab was used as the immunogen for this antibody (100% homologous in cow, dog and horse, and 94% homologous in mouse and rat).

    免疫原

    Amino acids 175-211 of human TIMP3 Ab was used as the immunogen for this antibody (100% homologous in cow, dog and horse, and 94% homologous in mouse and rat).
  • 应用备注

    FACS: use antibody at 0.5-1 μg/million cells
    IF: 1-2 μg/mL
    WB: 0.5-1 μg/mL
    IP: 1-2 μg/500 μg protein lysate
    Immunohistochemistry (FFPE): 1-2 μg/mL for 30 minutes at RT (1)
    Prediluted format: incubate for 30 min at RT (2)

    限制

    仅限研究用
  • 缓冲液

    In 1X PBS ( pH 7.4), BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原

    TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))

    别名

    Metalloproteinase inhibitor 3

    背景

    Target Description: TIMP3 (tissue inhibitor of metalloproteinases 3), along with family members TIMP1, TIMP2, and TIMP4, are inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix (ECM). An imbalance between MMPs and the associated TIMPs may play a significant role in the invasive phenotype of malignant tumors. TIMP 's inhibit the proteolytic invasiveness of tumor cells and normal placental trophoblast cells. TIMP3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes.

    Gene Symbol: TIMP3

    基因ID

    7078

    UniProt

    P35625
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