Transforming Protein Myb (AA 119-135) 抗体
The 小鼠 单克隆 anti-Transforming Protein Myb antibody is suitable to detect Transforming Protein Myb in samples from 人. It has been validated for FACS 和 IF.
产品编号 ABIN6294290
发货至:
中国
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Quick Overview for Transforming Protein Myb (AA 119-135) 抗体 (ABIN6294290)
抗原
Transforming Protein Myb
适用
人
宿主
小鼠
克隆类型
单克隆
应用范围
Flow Cytometry (FACS), Immunofluorescence (IF)
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抗原表位
- AA 119-135
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原理
- Mouse anti-Human c-Myb Antibody [Sodium Azide Free]
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特异性
- Nuclear
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纯化方法
- Amino acids 119-135 (RRKVEQEGYPQESSKAG) from the human protein were used as the immunogen for this c-Myb antibody.
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免疫原
- Amino acids 119-135 (RRKVEQEGYPQESSKAG) from the human protein were used as the immunogen for this c-Myb antibody.
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应用备注
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Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL -
限制
- 仅限研究用
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缓冲液
- In 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- Transforming Protein Myb
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背景
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Target Description: The highly leukemogenic avian retrovirus E26 contains two oncogenes, v-Myb and v-Ets, which are expressed together as a fusion protein. The cellular homolog of v-Myb, designated c-Myb, encodes a transcription factor. Deletion or disruption of a negative regulatory domain mapping within the carboxy-terminal domain of c-Myb results in enhanced transactivating capacity and in parallel, leads to activation of its ability to transform hemopoietic cells. c-Myb is expressed preferentially, but not exclusively, in immature hemopoietic cells and its expression decreases as cells differentiate.
Gene Symbol: V-MYB
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UniProt
- P01104
抗原
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