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FLI1 抗体 (AA 107-216)

This anti-FLI1 antibody is a 小鼠 单克隆 antibody detecting FLI1 in WB, IF 和 FACS. Suitable for 人.
产品编号 ABIN6294274
发货至: 中国

Quick Overview for FLI1 抗体 (AA 107-216) (ABIN6294274)

抗原

See all FLI1 抗体
FLI1 (Friend Leukemia Virus Integration 1 (FLI1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This FLI1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
  • 抗原表位

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    AA 107-216

    原理

    Mouse anti-Human FLI1 Antibody [Sodium Azide Free]

    特异性

    Nuclear

    纯化方法

    Human partial recombinant protein (amino acids 107-216) was used as the immunogen for this FLI1 antibody.

    免疫原

    Human partial recombinant protein (amino acids 107-216) was used as the immunogen for this FLI1 antibody.
  • 应用备注

    Western blot: 1-2 μg/m,l
    FACS: 0.5-1 μg/10^6 cells
    IF: 1-2 μg/mL

    限制

    仅限研究用
  • 缓冲液

    In 1X PBS ( pH 7.4), BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原

    FLI1 (Friend Leukemia Virus Integration 1 (FLI1))

    别名

    Friend leukemia integration 1 transcription factor

    背景

    Target Description: Friend leukemia integration 1 is a member of the ETS family of DNA binding transcription factors that is involved in cellular proliferation and tumorigenesis. Members of the Ets gene family share a highly conserved carboxy-terminal domain containing a sequence related to the SV40 large T antigen nuclear localization signal sequence. Approximately 90 % of Ewing's Sarcoma (EWS) / Primitive Neuroectodermal Tumors (PNET) have a specific translocation, t(11,22)(q24,q12), which results in fusion of EWS to Fli-1, and production of an EWS-Fli-1 fusion protein. Among normal tissues only endothelial cells and small lymphocytes express Fli-1. This protein is expressed in majority of vascular tumors including angiosarcomas, hemangioendotheliomas, hemangiomas, and Kaposi's Sarcomas. High sensitivity and specificity of Fli-1 equals to or exceeds that of the established vascular markers like CD31, CD34, and Factor VIII.

    Gene Symbol: FLI1

    基因ID

    2313

    UniProt

    Q01543
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