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Mesothelin 抗体 (AA 37-296)

Name: Mesothelin 抗体 (AA 37-296)
SKU: ABIN6290624
Availability: OutOfStock

This anti-Mesothelin antibody is a 兔多克隆 antibody detecting Mesothelin in WB, IHC 和 IF. Suitable for 人和大鼠.

Immunohistochemistry of paraffin-embedded rat kidney using MSLN Antibody (ABIN6290624) at dilution of 1:100 (40x lens). (Mesothelin 抗体 (AA 37-296))

IHC

1 image

产品编号 ABIN6290624

发货至: 中国

Quick Overview for Mesothelin 抗体 (AA 37-296) (ABIN6290624)

抗原

See all Mesothelin (MSLN) 抗体

Mesothelin (MSLN)

适用

人, 大鼠

宿主

兔

克隆类型

多克隆

标记

This Mesothelin antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Discover our top product MSLN Primary Antibody

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AA 37-296

纯化方法

Affinity purification

免疫原

Recombinant fusion protein containing a sequence corresponding to amino acids 37-296 of human MSLN (NP_001170826.1)

亚型

IgG
anti-Mesothelin (MSLN) (AA 273-407) antibody
MSLN 适用: 人 IHC (f) 宿主: 小鼠 Monoclonal MSLN-2131 unconjugated

anti-Mesothelin (MSLN) (AA 101-200) antibody
MSLN 适用: 人 ELISA, WB, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Mesothelin (MSLN) (AA 273-407) antibody
MSLN 适用: 人 IHC (f) 宿主: 小鼠 Monoclonal unconjugated

anti-Mesothelin (MSLN) (AA 37-286) antibody
MSLN 适用: 人, 猴 ELISA, WB, FACS 宿主: 小鼠 Monoclonal 5C11A4 unconjugated

anti-Mesothelin (MSLN) (AA 37-598) antibody
MSLN 适用: 人 ELISA, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated

anti-Mesothelin (MSLN) (AA 296-580) antibody
MSLN 适用: 人 ELISA, FACS 宿主: 兔 Monoclonal DM71 unconjugated Recombinant Antibody

anti-Mesothelin (MSLN) (AA 296-606) antibody
MSLN 适用: 人, 大鼠 ELISA, WB 宿主: 小鼠 Monoclonal 7E6A6 unconjugated

anti-Mesothelin (MSLN) (AA 37-286) antibody
MSLN 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 4H12F8 unconjugated

anti-Mesothelin (MSLN) (AA 1-62) antibody
MSLN 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Mesothelin (MSLN) antibody
MSLN 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:100

说明

Expressed in lung, Expressed at low levels in heart, placenta and kidney, Expressed in mesothelial cells, Highly expressed in mesotheliomas, ovarian cancers, and some squamous cell carcinomas (at protein level)

限制

仅限研究用
缓冲液

PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20C. Avoid freeze / thaw cycles.
抗原

Mesothelin (MSLN)

别名

MSLN

背景

This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

分子量

68.986 kDa

基因ID

10232

UniProt

Q13421

途径

EGFR Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process