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PICK1 抗体 (N-Term)

This anti-PICK1 antibody is a 兔 多克隆 antibody detecting PICK1 in WB, IHC 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6266358
发货至: 中国

Quick Overview for PICK1 抗体 (N-Term) (ABIN6266358)

抗原

See all PICK1 抗体
PICK1 (Protein Interacting With Protein Kinase C, alpha 1 (PICK1))

适用

  • 47
  • 35
  • 20
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 48
  • 11
  • 1

克隆类型

  • 41
  • 19
多克隆

标记

  • 35
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PICK1 antibody is un-conjugated

应用范围

  • 43
  • 25
  • 22
  • 11
  • 9
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

    • 8
    • 8
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    特异性

    PICK1 Antibody detects endogenous levels of total PICK1.

    预测反应

    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human PICK1, corresponding to a region within N-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    PICK1 (Protein Interacting With Protein Kinase C, alpha 1 (PICK1))

    别名

    PICK1

    背景

    Description: Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel. Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex, the function is competetive with nucleation promoting factors and is linked to neuronal morphology regulation and AMPA receptor (AMPAR) endocytosis. Via interaction with the Arp2/3 complex involved in regulation of synaptic plasicity of excitatory synapses and required for spine shrinkage during long-term depression (LTD). Involved in regulation of astrocyte morphology, antagonistic to Arp2/3 complex activator WASL/N-WASP function.

    Gene: PICK1

    分子量

    47kDa

    基因ID

    9463

    UniProt

    Q9NRD5
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