TRIM63 抗体 (N-Term)
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北京 101111
Quick Overview for TRIM63 抗体 (N-Term) (ABIN6266286)
抗原
See all TRIM63 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- TRIM63 Antibody detects endogenous levels of total TRIM63.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human TRIM63, corresponding to a region within N-terminal amino acids.
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亚型
- IgG
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anti-Tripartite Motif Containing 63 (TRIM63) (AA 1-353) antibody
TRIM63 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 63 (TRIM63) (AA 254-352) antibodyTRIM63 适用: 人 WB, ELISA, IF, RNAi 宿主: 小鼠 Monoclonal 6G6 unconjugated
anti-Tripartite Motif Containing 63 (TRIM63) (AA 293-304) antibodyTRIM63 适用: 人 ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 7B8E1 unconjugated
anti-Tripartite Motif Containing 63 (TRIM63) (AA 251-353) antibodyTRIM63 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 63 (TRIM63) (AA 254-352) antibodyTRIM63 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Tripartite Motif Containing 63 (TRIM63) (N-Term) antibodyVerified TRIM63 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Tripartite Motif Containing 63 (TRIM63) (AA 1-353) antibodyTRIM63 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Tripartite Motif Containing 63 (TRIM63) (AA 251-300) antibodyTRIM63 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 豚鼠, 兔, 猴, Bat, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:100, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- TRIM63 (Tripartite Motif Containing 63 (TRIM63))
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别名
- TRIM63
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背景
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Description: E3 ubiquitin ligase. Mediates the ubiquitination and subsequent proteasomal degradation of CKM, GMEB1 and HIBADH. Regulates the proteasomal degradation of muscle proteins under amino acid starvation, where muscle protein is catabolized to provide other organs with amino acids. Inhibits de novo skeletal muscle protein synthesis under amino acid starvation. Regulates proteasomal degradation of cardiac troponin I/TNNI3 and probably of other sarcomeric-associated proteins. May play a role in striated muscle atrophy and hypertrophy by regulating an anti-hypertrophic PKC-mediated signaling pathway. May regulate the organization of myofibrils through TTN in muscle cells.
Gene: TRIM63
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分子量
- 40kDa
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基因ID
- 84676
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UniProt
- Q969Q1
抗原
-
