ZNRF1 抗体 (Internal Region)
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北京 101111
Quick Overview for ZNRF1 抗体 (Internal Region) (ABIN6266142)
抗原
See all ZNRF1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- ZNRF1 Antibody detects endogenous levels of total ZNRF1.
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预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human ZNRF1, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Zinc and Ring Finger Protein 1 (ZNRF1) (Internal Region) antibody
Verified ZNRF1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Zinc and Ring Finger Protein 1 (ZNRF1) (AA 74-178) antibodyZNRF1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1H4 unconjugated
anti-Zinc and Ring Finger Protein 1 (ZNRF1) (AA 1-227) antibodyZNRF1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Zinc and Ring Finger Protein 1 (ZNRF1) (AA 74-179) antibodyZNRF1 适用: 人 WB, ELISA, IHC (p), IHC 宿主: 小鼠 Monoclonal 1H4 unconjugated
anti-Zinc and Ring Finger Protein 1 (ZNRF1) (N-Term) antibodyZNRF1 适用: 人, 小鼠, 大鼠, Cow, 斑马鱼, 豚鼠, 兔, Pig, Bat, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc and Ring Finger Protein 1 (ZNRF1) (N-Term) antibodyZNRF1 适用: 人, 小鼠, 大鼠, 斑马鱼, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc and Ring Finger Protein 1 (ZNRF1) (N-Term) antibodyZNRF1 适用: 人, 小鼠, 大鼠, Cow, 斑马鱼, 豚鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- ZNRF1 (Zinc and Ring Finger Protein 1 (ZNRF1))
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别名
- ZNRF1
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背景
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Description: E3 ubiquitin-protein ligase that mediates the ubiquitination of AKT1 and GLUL, thereby playing a role in neuron cells differentiation. Plays a role in the establishment and maintenance of neuronal transmission and plasticity. Regulates Schwann cells differentiation by mediating ubiquitination of GLUL. Promotes neurodegeneration by mediating 'Lys-48'-linked polyubiquitination and subsequent degradation of AKT1 in axons: degradation of AKT1 prevents AKT1-mediated phosphorylation of GSK3B, leading to GSK3B activation and phosphorylation of DPYSL2/CRMP2 followed by destabilization of microtubule assembly in axons (Probable).
Gene: ZNRF1
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分子量
- 24 kDa
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基因ID
- 84937
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UniProt
- Q8ND25
抗原
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