ZNF598 抗体 (N-Term)
Quick Overview for ZNF598 抗体 (N-Term) (ABIN6266100)
抗原
See all ZNF598 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- ZFP598 Antibody detects endogenous levels of total ZFP598.
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预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Dog,Chicken,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human ZFP598, corresponding to a region within N-terminal amino acids.
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亚型
- IgG
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anti-Zinc Finger Protein 598 (ZNF598) (AA 28-126) antibody
ZNF598 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Zinc Finger Protein 598 (ZNF598) (AA 28-126) antibodyZNF598 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 1E2 unconjugated
anti-Zinc Finger Protein 598 (ZNF598) (AA 398-447) antibodyZNF598 适用: 人, 大鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 598 (ZNF598) (AA 578-627) antibodyZNF598 适用: 人, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 598 (ZNF598) (AA 120-420) antibodyZNF598 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 598 (ZNF598) (Middle Region) antibodyZNF598 适用: 人, 小鼠, 大鼠, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 598 (ZNF598) (Middle Region) antibodyZNF598 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- ZNF598 (Zinc Finger Protein 598 (ZNF598))
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别名
- ZNF598
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背景
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Description: E3 ubiquitin-protein ligase that plays a key role in the ribosome quality control (RQC), a pathway that takes place when a ribosome has stalled during translation (PubMed:28065601, PubMed:28132843). Required for ribosomes to terminally stall during translation of poly(A) sequences by mediating monoubiquitination of 40S ribosomal protein RPS10/eS10, RPS20/uS10 and RPS3/uS3 (PubMed:28065601, PubMed:28132843). Stalling precludes synthesis of a long poly-lysine tail and initiates the RQC pathway to degrade the potentially detrimental aberrant nascent polypeptide (PubMed:28065601, PubMed:28132843). Also acts as a component of the 4EHP-GYF2 complex, a multiprotein complex that acts as a repressor of translation initiation (PubMed:22751931).
Gene: ZNF598
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分子量
- 98 kDa
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基因ID
- 90850
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UniProt
- Q86UK7
抗原
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