ZEB1 抗体 (Internal Region)
(3 references)Quick Overview for ZEB1 抗体 (Internal Region) (ABIN6266096)
抗原
See all ZEB1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- ZEB1 Antibody detects endogenous levels of total ZEB1.
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预测反应
- Pig,Bovine,Sheep,Rabbit,Dog,Chicken,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human ZEB1, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Zinc Finger E-Box Binding Homeobox 1 (ZEB1) (AA 967-1108) antibody
ZEB1 适用: 人 IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 2A8A6 unconjugated
anti-Zinc Finger E-Box Binding Homeobox 1 (ZEB1) (AA 801-900) antibodyZEB1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4C4 unconjugated
anti-Zinc Finger E-Box Binding Homeobox 1 (ZEB1) (N-Term) antibodyZEB1 适用: 人, 小鼠, 大鼠, 兔, 犬, Cow, 豚鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger E-Box Binding Homeobox 1 (ZEB1) (AA 1-260) antibodyZEB1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger E-Box Binding Homeobox 1 (ZEB1) antibodyKO Validated ZEB1 适用: 人 WB, IF, IP, ICC, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger E-Box Binding Homeobox 1 (ZEB1) antibodyZEB1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger E-Box Binding Homeobox 1 (ZEB1) (N-Term) antibodyZEB1 适用: 人, 小鼠, 大鼠, 兔, 犬, Cow, Pig, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger E-Box Binding Homeobox 1 (ZEB1) (Internal Region) antibodyVerified ZEB1 适用: 人, 小鼠 WB, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Zinc Finger E-Box Binding Homeobox 1 (ZEB1) (N-Term) antibodyZEB1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger E-Box Binding Homeobox 1 (ZEB1) (AA 904-1124) antibodyZEB1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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: "MicroRNA-139-5p affects cisplatin sensitivity in human nasopharyngeal carcinoma cells by regulating the epithelial-to-mesenchymal transition." in: Gene, Vol. 652, pp. 48-58, (2018) (PubMed).
: "EGCG regulates the cross-talk between JWA and topoisomerase IIα in non-small-cell lung cancer (NSCLC) cells." in: Scientific reports, Vol. 5, pp. 11009, (2016) (PubMed).
: "MicroRNA-181a regulates epithelial-mesenchymal transition by targeting PTEN in drug-resistant lung adenocarcinoma cells." in: International journal of oncology, Vol. 47, Issue 4, pp. 1379-92, (2016) (PubMed).
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: "MicroRNA-139-5p affects cisplatin sensitivity in human nasopharyngeal carcinoma cells by regulating the epithelial-to-mesenchymal transition." in: Gene, Vol. 652, pp. 48-58, (2018) (PubMed).
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- ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))
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别名
- ZEB1
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背景
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Description: Acts as a transcriptional repressor. Inhibits interleukin-2 (IL-2) gene expression. Enhances or represses the promoter activity of the ATP1A1 gene depending on the quantity of cDNA and on the cell type. Represses E-cadherin promoter and induces an epithelial-mesenchymal transition (EMT) by recruiting SMARCA4/BRG1. Represses BCL6 transcription in the presence of the corepressor CTBP1. Positively regulates neuronal differentiation. Represses RCOR1 transcription activation during neurogenesis. Represses transcription by binding to the E box (5'-CANNTG-3'). Promotes tumorigenicity by repressing stemness-inhibiting microRNAs.
Gene: ZEB1
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分子量
- 124kDa
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基因ID
- 6935
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UniProt
- P37275
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途径
- Regulation of Muscle Cell Differentiation
抗原
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