WWP1 抗体 (Internal Region)
Quick Overview for WWP1 抗体 (Internal Region) (ABIN6266055)
抗原
See all WWP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- WWP1 Antibody detects endogenous levels of total WWP1.
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预测反应
- Pig,Zebrafish,Bovine,Horse,Rabbit,Dog,Chicken
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human WWP1, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1) (AA 152-260) antibody
WWP1 适用: 人 WB, ELISA, IP, IF, IHC (p) 宿主: 小鼠 Monoclonal 1A7 unconjugated
anti-WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1) antibodyWWP1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1) (AA 152-260) antibodyWWP1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2B7 unconjugated
anti-WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1) (AA 1-260) antibodyWWP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1) antibodyWWP1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1) (AA 152-260) antibodyWWP1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1) (AA 1-922) antibodyWWP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1) (AA 152-261) antibodyWWP1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1A7 unconjugated
anti-WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1) (N-Term) antibodyWWP1 适用: 人, 小鼠, Cow, 犬, 豚鼠, 兔, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1) (N-Term) antibodyWWP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- WWP1 (WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1))
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别名
- WWP1
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背景
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Description: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Ubiquitinates ERBB4 isoforms JM-A CYT-1 and JM-B CYT-1, KLF2, KLF5 and TP63 and promotes their proteasomal degradation. Ubiquitinates RNF11 without targeting it for degradation. Ubiquitinates and promotes degradation of TGFBR1, the ubiquitination is enhanced by SMAD7. Ubiquitinates SMAD6 and SMAD7. Ubiquitinates and promotes degradation of SMAD2 in response to TGF-beta signaling, which requires interaction with TGIF.
Gene: WWP1
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分子量
- 95 kDa
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基因ID
- 11059
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UniProt
- Q9H0M0
抗原
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