WNK3 抗体 (C-Term)
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北京 101111
Quick Overview for WNK3 抗体 (C-Term) (ABIN6266034)
抗原
See all WNK3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- WNK3 Antibody detects endogenous levels of total WNK3.
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预测反应
- Pig,Horse,Rabbit,Dog
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human WNK3, corresponding to a region within C-terminal amino acids.
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亚型
- IgG
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anti-WNK Lysine Deficient Protein Kinase 3 (WNK3) (AA 451-550) antibody
WNK3 适用: 人, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-WNK Lysine Deficient Protein Kinase 3 (WNK3) (AA 500-600) antibodyWNK3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-WNK Lysine Deficient Protein Kinase 3 (WNK3) antibodyWNK3 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-WNK Lysine Deficient Protein Kinase 3 (WNK3) (AA 1-100) antibodyWNK3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4H5 unconjugated
anti-WNK Lysine Deficient Protein Kinase 3 (WNK3) (AA 1018-1181) antibodyWNK3 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-WNK Lysine Deficient Protein Kinase 3 (WNK3) (AA 1-100) antibodyWNK3 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-WNK Lysine Deficient Protein Kinase 3 (WNK3) (AA 431-480) antibodyWNK3 适用: 人, 小鼠, Bat, Cow, 犬, 豚鼠, 马, 猴, Pig, 兔 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-WNK Lysine Deficient Protein Kinase 3 (WNK3) antibodyWNK3 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-WNK Lysine Deficient Protein Kinase 3 (WNK3) (N-Term) antibodyWNK3 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-WNK Lysine Deficient Protein Kinase 3 (WNK3) (AA 1586-1616), (C-Term) antibodyWNK3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB3339 unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- WNK3 (WNK Lysine Deficient Protein Kinase 3 (WNK3))
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别名
- WNK3
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背景
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Description: Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively (PubMed:16275913, PubMed:16275911, PubMed:16357011). Phosphorylates WNK4. Regulates the phosphorylation of SLC12A1 and SLC12A2. Increases Ca2+ influx mediated by TRPV5 and TRPV6 by enhancing their membrane expression level via a kinase-dependent pathway (PubMed:18768590). Inhibits the activity of KCNJ1 by decreasing its expression at the cell membrane in a non-catalytic manner.
Gene: WNK3
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分子量
- 198kDa
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基因ID
- 65267
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UniProt
- Q9BYP7
抗原
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