USP9X 抗体 (N-Term)
Quick Overview for USP9X 抗体 (N-Term) (ABIN6265937)
抗原
See all USP9X 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- USP9X Antibody detects endogenous levels of total USP9X.
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预测反应
- Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human USP9X, corresponding to a region within N-terminal amino acids.
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亚型
- IgG
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anti-Ubiquitin Specific Peptidase 9, X-Linked (USP9X) (AA 2246-2570) antibody
USP9X 适用: 人, 小鼠, 大鼠, 犬, 猴 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2G7 unconjugated
anti-Ubiquitin Specific Peptidase 9, X-Linked (USP9X) (AA 1-90) antibodyUSP9X 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1C4 unconjugated
anti-Ubiquitin Specific Peptidase 9, X-Linked (USP9X) (AA 2360-2484), (C-Term) antibodyUSP9X 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 9, X-Linked (USP9X) (AA 2246-2570) antibodyUSP9X 适用: 人 WB 宿主: 小鼠 Monoclonal 1D7 unconjugated
anti-Ubiquitin Specific Peptidase 9, X-Linked (USP9X) (C-Term) antibodyUSP9X 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 9, X-Linked (USP9X) antibodyUSP9X 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 9, X-Linked (USP9X) (AA 1-90) antibodyUSP9X 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 9, X-Linked (USP9X) (C-Term) antibodyUSP9X 适用: 人, 大鼠, 犬, Cow, Pig, 兔, Bat, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- USP9X (Ubiquitin Specific Peptidase 9, X-Linked (USP9X))
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别名
- USP9X
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背景
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Description: Deubiquitinase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May therefore play an important regulatory role at the level of protein turnover by preventing degradation of proteins through the removal of conjugated ubiquitin. Specifically hydrolyzes 'Lys-48'-, 'Lys-29'- and 'Lys-33'-linked polyubiquitins chains. Essential component of TGF-beta/BMP signaling cascade. Specifically deubiquitinates monoubiquitinated SMAD4, opposing the activity of E3 ubiquitin-protein ligase TRIM33. Deubiquitinates alkylation repair enzyme ALKBH3. OTUD4 recruits USP7 and USP9X to stabilize ALKBH3, thereby promoting the repair of alkylated DNA lesions (PubMed:25944111). Regulates chromosome alignment and segregation in mitosis by regulating the localization of BIRC5/survivin to mitotic centromeres. Involved in axonal growth and neuronal cell migration (PubMed:16322459, PubMed:18254724, PubMed:19135894, PubMed:24607389).
Gene: USP9X
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分子量
- 260-290 kDa
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基因ID
- 8239
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UniProt
- Q93008
抗原
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