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USP6 抗体 (C-Term)

This 兔 多克隆 antibody specifically detects USP6 in WB 和 IHC. It exhibits reactivity toward 人, 大鼠 和 小鼠.
产品编号 ABIN6265934
发货至: 中国
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Quick Overview for USP6 抗体 (C-Term) (ABIN6265934)

抗原

See all USP6 抗体
USP6 (Ubiquitin Specific Peptidase 6 (USP6))

适用

  • 29
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
人, 大鼠, 小鼠

宿主

  • 23
  • 4
  • 2
兔

克隆类型

  • 25
  • 4
多克隆

标记

  • 15
  • 4
  • 3
  • 3
  • 2
  • 2
This USP6 antibody is un-conjugated

应用范围

  • 23
  • 17
  • 8
  • 8
  • 4
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 12
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    原理

    USP6 Antibody

    特异性

    USP6 Antibody detects endogenous levels of total USP6

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human USP6, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    IHC 1:50-1:200,WB 1:1000-3000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    USP6 (Ubiquitin Specific Peptidase 6 (USP6))

    别名

    USP6

    背景

    Description: Deubiquitinase with an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. Catalyzes its own deubiquitination. In vitro, isoform 2, but not isoform 3, shows deubiquitinating activity. Promotes plasma membrane localization of ARF6 and selectively regulates ARF6-dependent endocytic protein trafficking. Is able to initiate tumorigenesis by inducing the production of matrix metalloproteinases following NF-kappa-B activation.

    Gene: USP6

    分子量

    159 kDa

    基因ID

    9098

    UniProt

    P35125
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