USP51 抗体
Quick Overview for USP51 抗体 (ABIN6265932)
抗原
适用
宿主
克隆类型
标记
应用范围
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特异性
- USP51 Antibody detects endogenous levels of total USP51
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human USP51
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亚型
- IgG
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应用备注
- WB 1:1000-3000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
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有效期
- 12 months
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- USP51 (Ubiquitin Specific Peptidase 51 (USP51))
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别名
- USP51
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背景
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Description: Specifically deubiquitinates 'Lys-14' (H2AK13Ub) and 'Lys-16'(H2AK15Ub) of histone H2A regulating the DNA damage response at double-strand breaks (DSBs) (PubMed:27083998). USP51 is recruited to chromatin after DNA damage and regulates the dynamic assembly/disassembly of TP53BP1 and BRCA1. Exhibits also activity for 'Lys-27' or 'Lys-63'-linked di-ubiquitin (PubMed:27083998).
Gene: USP51
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分子量
- 80 kDa
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基因ID
- 158880
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UniProt
- Q70EK9
抗原
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