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USP51 抗体 (Internal Region)

The 兔 多克隆 anti-USP51 antibody is suitable to detect USP51 in samples from 人, 小鼠, 大鼠 和 猴. It has been validated for WB.
产品编号 ABIN6265932
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for USP51 抗体 (Internal Region) (ABIN6265932)

抗原

USP51 (Ubiquitin Specific Peptidase 51 (USP51))

适用

人, 小鼠, 大鼠, 猴

宿主

  • 11
  • 1

克隆类型

  • 12
多克隆

标记

  • 5
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This USP51 antibody is un-conjugated

应用范围

  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 2
    • 1
    • 1
    Internal Region

    原理

    USP51 Antibody

    特异性

    USP51 Antibody detects endogenous levels of total USP51

    预测反应

    Pig,Horse,Rabbit

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human USP51, corresponding to a region within the internal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:1000-3000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    USP51 (Ubiquitin Specific Peptidase 51 (USP51))

    别名

    USP51

    背景

    Description: Specifically deubiquitinates 'Lys-14' (H2AK13Ub) and 'Lys-16'(H2AK15Ub) of histone H2A regulating the DNA damage response at double-strand breaks (DSBs) (PubMed:27083998). USP51 is recruited to chromatin after DNA damage and regulates the dynamic assembly/disassembly of TP53BP1 and BRCA1. Exhibits also activity for 'Lys-27' or 'Lys-63'-linked di-ubiquitin (PubMed:27083998).

    Gene: USP51

    分子量

    80 kDa

    基因ID

    158880

    UniProt

    Q70EK9
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