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USP16 抗体 (N-Term)

This anti-USP16 antibody is a 兔 多克隆 antibody detecting USP16 in WB, ELISA, IHC, IF 和 ICC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6265912
发货至: 中国

Quick Overview for USP16 抗体 (N-Term) (ABIN6265912)

抗原

See all USP16 抗体
USP16 (Ubiquitin Specific Peptidase 16 (USP16))

适用

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  • 11
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  • 1
人, 小鼠, 大鼠

宿主

  • 45
  • 3
  • 1

克隆类型

  • 48
  • 1
多克隆

标记

  • 26
  • 5
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  • 3
  • 3
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  • 1
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  • 1
This USP16 antibody is un-conjugated

应用范围

  • 38
  • 24
  • 11
  • 5
  • 4
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

    • 10
    • 7
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    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
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    N-Term

    特异性

    USP16 Antibody detects endogenous levels of total USP16.

    预测反应

    Pig,Bovine,Horse,Sheep,Rabbit,Dog

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human USP16, corresponding to a region within N-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:1000-3000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    USP16 (Ubiquitin Specific Peptidase 16 (USP16))

    别名

    USP16

    背景

    Description: Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3 (H3S10ph), and is required for chromosome segregation when cells enter into mitosis. In resting B- and T-lymphocytes, phosphorylation by AURKB leads to enhance its activity, thereby maintaining transcription in resting lymphocytes. Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B.

    Gene: USP16

    分子量

    94 kDa

    基因ID

    10600

    UniProt

    Q9Y5T5
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