Urm1 抗体 (Internal Region)
Quick Overview for Urm1 抗体 (Internal Region) (ABIN6265904)
抗原
See all Urm1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- URM1 Antibody detects endogenous levels of total URM1.
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预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human URM1, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Ubiquitin Related Modifier 1 (Urm1) antibody
Urm1 适用: 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Related Modifier 1 (Urm1) (AA 1-63) antibodyUrm1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Related Modifier 1 (Urm1) antibodyUrm1 适用: Saccharomyces cerevisiae WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000-3000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- Urm1 (Ubiquitin Related Modifier 1 (Urm1))
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别名
- URM1
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背景
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Description: Acts as a sulfur carrier required for 2-thiolation of mcm5S2U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm5S2U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as MOCS3, ATPBD3, CTU2, USP15 and CAS. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
Gene: URM1
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分子量
- 11 kDa
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基因ID
- 81605
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UniProt
- Q9BTM9
抗原
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