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UFM1 抗体 (Internal Region)

The 兔 多克隆 anti-UFM1 antibody is suitable to detect UFM1 in samples from 人 和 小鼠. It has been validated for WB 和 ELISA.
产品编号 ABIN6265872
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for UFM1 抗体 (Internal Region) (ABIN6265872)

抗原

See all UFM1 抗体
UFM1 (Ubiquitin-Fold Modifier 1 (UFM1))

适用

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人, 小鼠

宿主

  • 37

克隆类型

  • 21
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多克隆

标记

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This UFM1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    Internal Region

    特异性

    UFM1 Antibody detects endogenous levels of total UFM1.

    预测反应

    Pig,Zebrafish,Bovine,Horse,Sheep,Dog,Chicken,Xenopus

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human UFM1, corresponding to a region within the internal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    UFM1 (Ubiquitin-Fold Modifier 1 (UFM1))

    别名

    UFM1

    背景

    Description: Ubiquitin-like modifier which can be covalently attached via an isopeptide bond to substrate proteins as a monomer or a lysine-linked polymer (PubMed:15071506, PubMed:20018847). The so-called ufmylation, requires the UFM1-activating E1 enzyme UBA5, the UFM1-conjugating E2 enzyme UFC1, and the UFM1-ligase E3 enzyme UFL1 (PubMed:15071506, PubMed:20018847). This post-translational modification on lysine residues of proteins may play a crucial role in a number of cellular processes (PubMed:15071506, PubMed:20018847). TRIP4 ufmylation may for instance play a role in nuclear receptors-mediated transcription (PubMed:25219498). Other substrates may include DDRGK1 with which it may play a role in the cellular response to endoplasmic reticulum stress (Probable).

    Gene: UFM1

    分子量

    9 kDa

    基因ID

    51569

    UniProt

    P61960
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