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UBE2L3 抗体 (C-Term)

This 兔 多克隆 antibody specifically detects UBE2L3 in WB 和 ELISA. It exhibits reactivity toward 人 和 小鼠.
产品编号 ABIN6265850
发货至: 中国
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Quick Overview for UBE2L3 抗体 (C-Term) (ABIN6265850)

抗原

See all UBE2L3 抗体
UBE2L3 (Ubiquitin-Conjugating Enzyme E2L 3 (UBE2L3))

适用

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人, 小鼠

宿主

  • 69
  • 1
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克隆类型

  • 57
  • 14
多克隆

标记

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This UBE2L3 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    C-Term

    特异性

    UBE2L3 Antibody detects endogenous levels of total UBE2L3.

    预测反应

    Pig,Bovine,Sheep,Rabbit,Dog,Chicken,Xenopus

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human UBE2L3, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    UBE2L3 (Ubiquitin-Conjugating Enzyme E2L 3 (UBE2L3))

    别名

    UBE2L3

    背景

    Description: Ubiquitin-conjugating enzyme E2 that specifically acts with HECT-type and RBR family E3 ubiquitin-protein ligases. Does not function with most RING-containing E3 ubiquitin-protein ligases because it lacks intrinsic E3-independent reactivity with lysine: in contrast, it has activity with the RBR family E3 enzymes, such as PRKN and ARIH1, that function like function like RING-HECT hybrids. Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'-linked polyubiquitination. Involved in the selective degradation of short-lived and abnormal proteins. Down-regulated during the S-phase it is involved in progression through the cell cycle. Regulates nuclear hormone receptors transcriptional activity. May play a role in myelopoiesis.

    Gene: UBE2L3

    分子量

    18 kDa

    基因ID

    7332

    UniProt

    P68036
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