UBE2L3 抗体 (C-Term)
Quick Overview for UBE2L3 抗体 (C-Term) (ABIN6265850)
抗原
See all UBE2L3 抗体适用
宿主
克隆类型
标记
应用范围
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                                            抗原表位
- C-Term
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                                            特异性
- UBE2L3 Antibody detects endogenous levels of total UBE2L3.
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                                            预测反应
- Pig,Bovine,Sheep,Rabbit,Dog,Chicken,Xenopus
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                                            纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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                                            免疫原
- A synthesized peptide derived from human UBE2L3, corresponding to a region within C-terminal amino acids.
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                                            亚型
- IgG
 
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                                            应用备注
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
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                                            限制
- 仅限研究用
 
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                                            状态
- Liquid
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                                            浓度
- 1 mg/mL
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                                            缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            储存条件
- -20 °C
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                                            储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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                                            有效期
- 12 months
 
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    - UBE2L3 (Ubiquitin-Conjugating Enzyme E2L 3 (UBE2L3))
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                                            别名
- UBE2L3
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                                            背景
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                        Description: Ubiquitin-conjugating enzyme E2 that specifically acts with HECT-type and RBR family E3 ubiquitin-protein ligases. Does not function with most RING-containing E3 ubiquitin-protein ligases because it lacks intrinsic E3-independent reactivity with lysine: in contrast, it has activity with the RBR family E3 enzymes, such as PRKN and ARIH1, that function like function like RING-HECT hybrids. Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'-linked polyubiquitination. Involved in the selective degradation of short-lived and abnormal proteins. Down-regulated during the S-phase it is involved in progression through the cell cycle. Regulates nuclear hormone receptors transcriptional activity. May play a role in myelopoiesis. Gene: UBE2L3 
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                                            分子量
- 18 kDa
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                                            基因ID
- 7332
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                                            UniProt
- P68036
 抗原
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