TXNIP 抗体 (Internal Region)
Our Local Distributor
北京 101111
Quick Overview for TXNIP 抗体 (Internal Region) (ABIN6265817)
抗原
See all TXNIP 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Internal Region
-
特异性
- TXNIP Antibody detects endogenous levels of total TXNIP.
-
预测反应
- Pig,Bovine,Sheep,Rabbit,Dog,Xenopus
-
纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
-
免疫原
- A synthesized peptide derived from human TXNIP, corresponding to a region within the internal amino acids.
-
亚型
- IgG
-
-
anti-Thioredoxin Interacting Protein (TXNIP) (AA 30-381) antibody
TXNIP 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin Interacting Protein (TXNIP) (AA 32-367) antibodyTXNIP 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin Interacting Protein (TXNIP) (C-Term) antibodyTXNIP 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 豚鼠, 绵羊 WB 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin Interacting Protein (TXNIP) (AA 1-30), (N-Term) antibodyTXNIP 适用: 人 WB 宿主: 兔 Polyclonal RB41554 unconjugated
anti-Thioredoxin Interacting Protein (TXNIP) (AA 116-145) antibodyTXNIP 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB30652 unconjugated
anti-Thioredoxin Interacting Protein (TXNIP) (AA 101-200) antibodyTXNIP 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin Interacting Protein (TXNIP) (C-Term) antibodyTXNIP 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 豚鼠, 绵羊, 猴, Bat, Pig, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin Interacting Protein (TXNIP) (AA 299-381) antibodyTXNIP 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin Interacting Protein (TXNIP) (AA 100-150) antibodyTXNIP 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin Interacting Protein (TXNIP) (AA 121-170) antibodyTXNIP 适用: 人, 犬, Cow, 猴 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
-
有效期
- 12 months
-
-
- TXNIP (Thioredoxin Interacting Protein (TXNIP))
-
别名
- TXNIP
-
背景
-
Description: May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. Acts as a suppressor of tumor cell growth. Inhibits the proteasomal degradation of DDIT4, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1).
Gene: TXNIP
-
分子量
- 50 kDa
-
基因ID
- 10628
-
UniProt
- Q9H3M7
-
途径
- Protein targeting to Nucleus, Platelet-derived growth Factor Receptor Signaling, Inflammasome
抗原
-
