TUT1 抗体 (N-Term)
Quick Overview for TUT1 抗体 (N-Term) (ABIN6265809)
抗原
See all TUT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- TUTase Antibody detects endogenous levels of total TUTase.
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预测反应
- Bovine,Horse,Rabbit,Dog
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human TUTase, corresponding to a region within N-terminal amino acids.
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亚型
- IgG
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anti-Terminal Uridylyl Transferase 1, U6 SnRNA-Specific (TUT1) antibody
TUT1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Terminal Uridylyl Transferase 1, U6 SnRNA-Specific (TUT1) (N-Term) antibodyTUT1 适用: 人, 小鼠, 犬, 豚鼠, 大鼠, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Terminal Uridylyl Transferase 1, U6 SnRNA-Specific (TUT1) (AA 253-302) antibodyTUT1 适用: 人, 犬, Cow, 豚鼠, 马, 猴, Pig, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Terminal Uridylyl Transferase 1, U6 SnRNA-Specific (TUT1) (AA 829-878) antibodyTUT1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Terminal Uridylyl Transferase 1, U6 SnRNA-Specific (TUT1) (N-Term) antibodyTUT1 适用: 人, 小鼠, 犬, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-Terminal Uridylyl Transferase 1, U6 SnRNA-Specific (TUT1) (AA 291-340) antibodyTUT1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Terminal Uridylyl Transferase 1, U6 SnRNA-Specific (TUT1) (N-Term) antibodyTUT1 适用: 人, 小鼠, 犬, Cow, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- TUT1 (Terminal Uridylyl Transferase 1, U6 SnRNA-Specific (TUT1))
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别名
- TUT1
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背景
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Description: Poly(A) polymerase that creates the 3'-poly(A) tail of specific pre-mRNAs. Localizes to nuclear speckles together with PIP5K1A and mediates polyadenylation of a select set of mRNAs, such as HMOX1. In addition to polyadenylation, it is also required for the 3'-end cleavage of pre-mRNAs: binds to the 3'UTR of targeted pre-mRNAs and promotes the recruitment and assembly of the CPSF complex on the 3'UTR of pre-mRNAs. In addition to adenylyltransferase activity, also has uridylyltransferase activity. However, the ATP ratio is higher than UTP in cells, suggesting that it functions primarily as a poly(A) polymerase. Acts as a specific terminal uridylyltransferase for U6 snRNA in vitro: responsible for a controlled elongation reaction that results in the restoration of the four 3'-terminal UMP-residues found in newly transcribed U6 snRNA. Not involved in replication-dependent histone mRNA degradation.
Gene: TUT1
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分子量
- 95kDa
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基因ID
- 64852
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UniProt
- Q9H6E5
抗原
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