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TRIM24 抗体 (C-Term)

This anti-TRIM24 antibody is a 兔 多克隆 antibody detecting TRIM24 in WB, ELISA, IHC, IF 和 ICC. Suitable for 人 和 小鼠.
产品编号 ABIN6265731
发货至: 中国

Quick Overview for TRIM24 抗体 (C-Term) (ABIN6265731)

抗原

See all TRIM24 抗体
TRIM24 (Tripartite Motif Containing 24 (TRIM24))

适用

  • 59
  • 24
  • 7
  • 6
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  • 3
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  • 2
  • 1
人, 小鼠

宿主

  • 54
  • 6
  • 1

克隆类型

  • 51
  • 10
多克隆

标记

  • 40
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
This TRIM24 antibody is un-conjugated

应用范围

  • 41
  • 21
  • 15
  • 8
  • 7
  • 5
  • 4
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

    • 8
    • 8
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    特异性

    TRIM24 Antibody detects endogenous levels of total TRIM24.

    预测反应

    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human TRIM24, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    TRIM24 (Tripartite Motif Containing 24 (TRIM24))

    别名

    TRIM24

    背景

    Description: Transcriptional coactivator that interacts with numerous nuclear receptors and coactivators and modulates the transcription of target genes. Interacts with chromatin depending on histone H3 modifications, having the highest affinity for histone H3 that is both unmodified at 'Lys-4' (H3K4me0) and acetylated at 'Lys-23' (H3K23ac). Has E3 protein-ubiquitin ligase activity. Promotes ubiquitination and proteasomal degradation of p53/TP53. Plays a role in the regulation of cell proliferation and apoptosis, at least in part via its effects on p53/TP53 levels. Up-regulates ligand-dependent transcription activation by AR, GCR/NR3C1, thyroid hormone receptor (TR) and ESR1. Modulates transcription activation by retinoic acid (RA) receptors, including RARA. Plays a role in regulating retinoic acid-dependent proliferation of hepatocytes (By similarity).

    Gene: TRIM24

    分子量

    117kDa

    基因ID

    8805

    UniProt

    O15164
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