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TRIM14 抗体 (C-Term)

This anti-TRIM14 antibody is a 兔 多克隆 antibody detecting TRIM14 in WB 和 IHC. Suitable for 人.
产品编号 ABIN6265727
发货至: 中国

Quick Overview for TRIM14 抗体 (C-Term) (ABIN6265727)

抗原

See all TRIM14 抗体
TRIM14 (Tripartite Motif Containing 14 (TRIM14))

适用

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宿主

  • 18
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克隆类型

  • 19
多克隆

标记

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This TRIM14 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    C-Term

    特异性

    TRIM14 Antibody detects endogenous levels of total TRIM14.

    预测反应

    Pig,Bovine,Rabbit

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human TRIM14, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    TRIM14 (Tripartite Motif Containing 14 (TRIM14))

    别名

    TRIM14

    背景

    Description: Plays a role in the innate immune defense against viruses. Facilitates the type I IFN response by interacting with MAVS at the outer mitochondria membrane and thereby recruiting NF-kappa-B essential modulator IKBKG/NEMO to the MAVS signalosome, leading to the activation of both the IFN regulatory factor 3/IRF3 and NF-kappa-B pathways (PubMed:24379373). Positively regulates the CGAS-induced type I interferon signaling pathway by stabilizing CGAS and inhibiting its autophagic degradation (PubMed:27666593).

    Gene: TRIM14

    分子量

    50 kDa

    基因ID

    9830

    UniProt

    Q14142
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