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TRIB3 抗体 (N-Term)

This anti-TRIB3 antibody is a 兔 多克隆 antibody detecting TRIB3 in WB, ELISA 和 IHC. Suitable for 人.
产品编号 ABIN6265726
发货至: 中国
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Quick Overview for TRIB3 抗体 (N-Term) (ABIN6265726)

抗原

See all TRIB3 抗体
TRIB3 (Tribbles Homolog 3 (Drosophila) (TRIB3))

适用

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宿主

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克隆类型

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多克隆

标记

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This TRIB3 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    N-Term

    特异性

    TRIB3 Antibody detects endogenous levels of total TRIB3.

    预测反应

    Pig,Bovine,Sheep

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human TRIB3, corresponding to a region within N-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    TRIB3 (Tribbles Homolog 3 (Drosophila) (TRIB3))

    别名

    TRIB3

    背景

    Description: Disrupts insulin signaling by binding directly to Akt kinases and blocking their activation. May bind directly to and mask the 'Thr-308' phosphorylation site in AKT1. Binds to ATF4 and inhibits its transcriptional activation activity. Interacts with the NF-kappa-B transactivator p65 RELA and inhibits its phosphorylation and thus its transcriptional activation activity. Interacts with MAPK kinases and regulates activation of MAP kinases. May play a role in programmed neuronal cell death but does not appear to affect non-neuronal cells. Does not display kinase activity. Inhibits the transcriptional activity of DDIT3/CHOP and is involved in DDIT3/CHOP-dependent cell death during ER stress. Can inhibit APOBEC3A editing of nuclear DNA.

    Gene: TRIB3

    分子量

    40 kDa

    基因ID

    57761

    UniProt

    Q96RU7

    途径

    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
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