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TPMT 抗体 (N-Term)

This anti-TPMT antibody is a 兔 多克隆 antibody detecting TPMT in WB, ELISA 和 IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6265692
发货至: 中国

Quick Overview for TPMT 抗体 (N-Term) (ABIN6265692)

抗原

See all TPMT 抗体
TPMT (Thiopurine S-Methyltransferase (TPMT))

适用

  • 46
  • 12
  • 12
  • 2
  • 2
人, 小鼠, 大鼠

宿主

  • 36
  • 10

克隆类型

  • 32
  • 14
多克隆

标记

  • 29
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This TPMT antibody is un-conjugated

应用范围

  • 35
  • 20
  • 20
  • 7
  • 6
  • 5
  • 3
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    N-Term

    特异性

    TPMT Antibody detects endogenous levels of total TPMT.

    预测反应

    Bovine,Horse,Rabbit

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human TPMT, corresponding to a region within N-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    TPMT (Thiopurine S-Methyltransferase (TPMT))

    别名

    TPMT

    背景

    Description: Catalyzes the S-methylation of thiopurine drugs such as 6-mercaptopurine (also called mercaptopurine, 6-MP or its brand name Purinethol) and 6-thioguanine (also called tioguanine or 6-TG) using S-adenosyl-L-methionine as the methyl donor (PubMed:657528, PubMed:18484748). TPMT activity modulates the cytotoxic effects of thiopurine prodrugs. A natural substrate for this enzyme has yet to be identified.

    Gene: TPMT

    分子量

    28kDa

    基因ID

    7172

    UniProt

    P51580
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