TJP3 抗体 (C-Term)
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北京 101111
Quick Overview for TJP3 抗体 (C-Term) (ABIN6265590)
抗原
See all TJP3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- TJP3 Antibody detects endogenous levels of total TJP3.
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预测反应
- Pig,Dog,Chicken
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human TJP3, corresponding to a region within C-terminal amino acids.
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亚型
- IgG
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anti-Tight Junction Protein 3 (Zona Occludens 3) (TJP3) (AA 868-952) antibody
TJP3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E8 unconjugated
anti-Tight Junction Protein 3 (Zona Occludens 3) (TJP3) (C-Term) antibodyTJP3 适用: 人, 犬 WB, IP, IHC, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tight Junction Protein 3 (Zona Occludens 3) (TJP3) (AA 868-952) antibodyTJP3 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Tight Junction Protein 3 (Zona Occludens 3) (TJP3) (AA 885-905), (C-Term) antibodyTJP3 适用: 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tight Junction Protein 3 (Zona Occludens 3) (TJP3) (AA 1-243) antibodyTJP3 适用: 大鼠 WB, IP, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- TJP3 (Tight Junction Protein 3 (Zona Occludens 3) (TJP3))
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别名
- TJP3
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背景
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Description: TJP1, TJP2, and TJP3 are closely related scaffolding proteins that link tight junction (TJ) transmembrane proteins such as claudins, junctional adhesion molecules, and occludin to the actin cytoskeleton (PubMed:16129888). The tight junction acts to limit movement of substances through the paracellular space and as a boundary between the compositionally distinct apical and basolateral plasma membrane domains of epithelial and endothelial cells. Binds and recruits PATJ to tight junctions where it connects and stabilizes apical and lateral components of tight junctions (PubMed:16129888). Promotes cell-cycle progression through the sequestration of cyclin D1 (CCND1) at tight junctions during mitosis which prevents CCND1 degradation during M-phase and enables S-phase transition (PubMed:21411630). With TJP1 and TJP2, participates to the junctional retention and stability of the transcription factor DBPA, but is not involved in its shuttling to the nucleus (By similarity). Contrary to TJP2, TJP3 is dispensable for individual viability, embryonic development, epithelial differentiation, and the establishment of TJs, at least in the laboratory environment (By similarity).
Gene: TJP3
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分子量
- 101 kDa
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基因ID
- 27134
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UniProt
- O95049
抗原
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