TELO2 抗体 (Internal Region)
Quick Overview for TELO2 抗体 (Internal Region) (ABIN6265516)
抗原
See all TELO2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- TELO2 Antibody detects endogenous levels of total TELO2.
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预测反应
- Pig,Bovine,Horse,Rabbit,Dog
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human TELO2, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-TEL2, Telomere Maintenance 2, Homolog (TELO2) (AA 786-812), (C-Term) antibody
TELO2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB24688 unconjugated
anti-TEL2, Telomere Maintenance 2, Homolog (TELO2) (AA 450-550) antibodyTELO2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- TELO2 (TEL2, Telomere Maintenance 2, Homolog (TELO2))
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别名
- TELO2
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背景
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Description: Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals. May be involved in telomere length regulation.
Gene: TELO2
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分子量
- 92 kDa
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基因ID
- 9894
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UniProt
- Q9Y4R8
抗原
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