TCTN1 抗体 (N-Term)
Quick Overview for TCTN1 抗体 (N-Term) (ABIN6265507)
抗原
See all TCTN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- TCTN1 Antibody detects endogenous levels of total TCTN1.
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预测反应
- Pig
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human TCTN1, corresponding to a region within N-terminal amino acids.
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亚型
- IgG
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anti-Tectonic Family Member 1 (TCTN1) (AA 130-310) antibody
TCTN1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Tectonic Family Member 1 (TCTN1) (N-Term) antibodyTCTN1 适用: 人, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- TCTN1 (Tectonic Family Member 1 (TCTN1))
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别名
- TCTN1
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背景
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Description: Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Regulator of Hedgehog (Hh), required for both activation and inhibition of the Hh pathway in the patterning of the neural tube. During neural tube development, it is required for formation of the most ventral cell types and for full Hh pathway activation. Functions in Hh signal transduction to fully activate the pathway in the presence of high Hh levels and to repress the pathway in the absence of Hh signals. Modulates Hh signal transduction downstream of SMO and RAB23 (By similarity).
Gene: TCTN1
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分子量
- 55-64kDa
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基因ID
- 79600
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UniProt
- Q2MV58
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途径
- Tube Formation
抗原
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